The No. 7 Fighting Irish host the No. 10 Hoosiers for a College Football Playoff first-round game. The winner meets Georgia in the quarterfinals at the Sugar Bowl on New Year's Day. The Indiana schools, located some 200 miles apart, last met in 1991.
A consequential Big Ten matchup pits the No. 2 Buckeyes (9-1, 6-1) against the No. 5 Hoosiers (10-0, 7-0). The winner will be in the driver's seat for a likely championship-game date with Oregon. Indiana's last victory over Ohio State came in 1988.