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Family Guy
This animated series features the adventures of the Griffin family. Endearingly ignorant Peter and his stay-at-home wife, Lois, reside in Quahog, R.I., and have three kids. Meg, the eldest child, is a social outcast, and teenage Chris is awkward and clueless when it comes to the opposite sex. The youngest, Stewie, is a genius baby who is bent on killing his mother and destroying the world. Brian, the talking dog, keeps Stewie in check while sipping martinis and sorting through his own issues.
S13, EP5 "Turkey Guys"
A drunken Brian and Peter devour the holiday turkey the night before Thanksgiving; Chris becomes the man of the house in Peter's absence.
S14, EP6 "Peter's Sister"
When Peter's sister, Karen (Kate McKinnon), visits for Thanksgiving, she acts like a bully; Brian and Stewie go on a cleanse.
S10, EP5 "Back to the Pilot"
Brian and Stewie travel back to the pilot episode of the series to change history.
S18, EP8 "Shanksgiving"
When Lois hosts a special Thanksgiving dinner for her family, Peter decides the best way to avoid it is to get arrested; a secret that Stewie has been keeping from everyone is revealed.
S20, EP10 "Christmas Crime"
When Mayor West's nativity scene is ruined, Brian is seen as the prime suspect.