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Family Guy
This animated series features the adventures of the Griffin family. Endearingly ignorant Peter and his stay-at-home wife, Lois, reside in Quahog, R.I., and have three kids. Meg, the eldest child, is a social outcast, and teenage Chris is awkward and clueless when it comes to the opposite sex. The youngest, Stewie, is a genius baby who is bent on killing his mother and destroying the world. Brian, the talking dog, keeps Stewie in check while sipping martinis and sorting through his own issues.
S4, EP16 "The Courtship of Stewie's Father"
Stewie steps up his efforts to kill Lois, who orders Peter to spend more time with him.
S4, EP17 "Fat Guy Strangler"
Lois learns she has a brother she has never met (Robert Downey Jr.), so she brings him home from a mental institution to live with her family.
S4, EP18 "The Father, the Son and the Holy Fonz"
When Peter's dad visits the Griffins, he tries to impose his religious beliefs on the family.
S4, EP19 "Brian Sings and Swings"
A near-death experience lands Brian in the hospital but infuses him with a new passion for life.
S20, EP10 "Christmas Crime"
When Mayor West's nativity scene is ruined, Brian is seen as the prime suspect.